Phieng Siliphaivanh

Affiliations

Computational and Structural Chemistry, Discovery Chemistry, and Quantitative Biosciences, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115, United States.

Publications (5)

Allosteric Modulation of Protein Arginine Methyltransferase 5 (PRMT5).

ACS medicinal chemistry letters

Avec: Rachel L Palte , Sebastian E Schneider , Michael D Altman , Robert P Hayes , Shuhei Kawamura , Brian M Lacey , My Sam Mansueto , Michael Reutershan , Phieng Siliphaivanh , Christopher Sondey , Haiyan Xu , Zangwei Xu , Yingchun Ye , Michelle R Machacek

Structure-Based Discovery of Proline-Derived Arginase Inhibitors with Improved Oral Bioavailability for Immuno-Oncology.

ACS medicinal chemistry letters

Avec: Min Lu , Hongjun Zhang , Derun Li , Matthew Childers , Qinglin Pu , Rachel L Palte , Symon Gathiaka , Thomas W Lyons , Anandan Palani , Peter W Fan , Peter Spacciapoli , J Richard Miller , Hyelim Cho , Mangeng Cheng , Kalyan Chakravarthy , Jennifer O'Neil , Padmanabhan Eangoor , Adam Beard , Hai-Young Kim , Josep Saurí , Hakan Gunaydin , David L Sloman , Phieng Siliphaivanh , Jared Cumming , Christian Fischer

The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer.

Journal of medicinal chemistry

Avec: Ryan V Quiroz , Michael H Reutershan , Sebastian E Schneider , David Sloman , Brian M Lacey , Brooke M Swalm , Charles S Yeung , Craig Gibeau , Daniel S Spellman , Danica A Rankic , Dapeng Chen , David Witter , Doug Linn , Erik Munsell , Guo Feng , Haiyan Xu , Jonathan M E Hughes , Jongwon Lim , Josep Saurí , Kristin Geddes , Murray Wan , My Sam Mansueto , Nicole E Follmer , Patrick S Fier , Phieng Siliphaivanh , Pierre Daublain , Rachel L Palte , Robert P Hayes , Sandra Lee , Shuhei Kawamura , Steven Silverman , Sulagna Sanyal , Timothy J Henderson , Yingchun Ye , Yuanwei Gao , Benjamin Nicholson , Michelle R Machacek

Identification of Potent Reverse Indazole Inhibitors for HPK1.

ACS medicinal chemistry letters

Avec: Elsie C Yu , Joey L Methot , Xavier Fradera , Charles A Lesburg , Brian M Lacey , Phieng Siliphaivanh , Ping Liu , Dustin M Smith , Zangwei Xu , Jennifer A Piesvaux , Shuhei Kawamura , Haiyan Xu , J Richard Miller , Mark Bittinger , Alexander Pasternak

Structural insights on ligand recognition at the human leukotriene B4 receptor 1.

Nature communications

Avec: Nairie Michaelian , Anastasiia Sadybekov , Élie Besserer-Offroy , Gye Won Han , Harini Krishnamurthy , Beata A Zamlynny , Xavier Fradera , Phieng Siliphaivanh , Jeremy Presland , Kerrie B Spencer , Stephen M Soisson , Petr Popov , Philippe Sarret , Vsevolod Katritch , Vadim Cherezov

Réseau de co-auteurs

Rachel L Palte 3 collaborations

Shuhei Kawamura 3 collaborations

Brian M Lacey 3 collaborations

Haiyan Xu 3 collaborations

Sebastian E Schneider 2 collaborations

Robert P Hayes 2 collaborations

My Sam Mansueto 2 collaborations

Zangwei Xu 2 collaborations

Yingchun Ye 2 collaborations

Michelle R Machacek 2 collaborations

J Richard Miller 2 collaborations

Josep Saurí 2 collaborations

Xavier Fradera 2 collaborations

Michael D Altman 1 collaboration

Michael Reutershan 1 collaboration

Christopher Sondey 1 collaboration

Min Lu 1 collaboration

Hongjun Zhang 1 collaboration

Derun Li 1 collaboration

Matthew Childers 1 collaboration

Qinglin Pu 1 collaboration

Symon Gathiaka 1 collaboration

Thomas W Lyons 1 collaboration

Anandan Palani 1 collaboration

Peter W Fan 1 collaboration

Peter Spacciapoli 1 collaboration

Hyelim Cho 1 collaboration

Mangeng Cheng 1 collaboration

Kalyan Chakravarthy 1 collaboration

Jennifer O'Neil 1 collaboration

Padmanabhan Eangoor 1 collaboration

Adam Beard 1 collaboration

Hai-Young Kim 1 collaboration

Hakan Gunaydin 1 collaboration

David L Sloman 1 collaboration

Jared Cumming 1 collaboration

Christian Fischer 1 collaboration

Ryan V Quiroz 1 collaboration

Michael H Reutershan 1 collaboration

David Sloman 1 collaboration

Brooke M Swalm 1 collaboration

Charles S Yeung 1 collaboration

Craig Gibeau 1 collaboration

Daniel S Spellman 1 collaboration

Danica A Rankic 1 collaboration

Dapeng Chen 1 collaboration

David Witter 1 collaboration

Doug Linn 1 collaboration

Erik Munsell 1 collaboration

Guo Feng 1 collaboration

Jonathan M E Hughes 1 collaboration

Jongwon Lim 1 collaboration

Kristin Geddes 1 collaboration

Murray Wan 1 collaboration

Nicole E Follmer 1 collaboration

Patrick S Fier 1 collaboration

Pierre Daublain 1 collaboration

Sandra Lee 1 collaboration

Steven Silverman 1 collaboration

Sulagna Sanyal 1 collaboration

Timothy J Henderson 1 collaboration

Yuanwei Gao 1 collaboration

Benjamin Nicholson 1 collaboration

Elsie C Yu 1 collaboration

Joey L Methot 1 collaboration

Charles A Lesburg 1 collaboration

Ping Liu 1 collaboration

Dustin M Smith 1 collaboration

Jennifer A Piesvaux 1 collaboration

Mark Bittinger 1 collaboration

Alexander Pasternak 1 collaboration

Nairie Michaelian 1 collaboration

Anastasiia Sadybekov 1 collaboration

Élie Besserer-Offroy 1 collaboration

Gye Won Han 1 collaboration

Harini Krishnamurthy 1 collaboration

Beata A Zamlynny 1 collaboration

Jeremy Presland 1 collaboration

Kerrie B Spencer 1 collaboration

Stephen M Soisson 1 collaboration

Petr Popov 1 collaboration

Philippe Sarret 1 collaboration

Vsevolod Katritch 1 collaboration

Vadim Cherezov 1 collaboration